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彼得 帕克（托比?马奎尔 Tobey Maguire 饰）只是美国一个平凡的高中生，当一次他被蜘蛛博物馆偷跑出来的变种蜘蛛咬了一口之后，彼得的生活彻底改变了。他变得和蜘蛛一样，拥有各种蜘蛛特有的超能力：从手指喷出粘力极强的蜘蛛丝、飞檐走壁等等。彼得兴奋异常，开始利用自己的超能力去赚钱。但当他最爱的叔叔被自己放走的罪犯杀死后，彼得发誓要用自己的超能力去打击犯罪。 彼得好友哈利的父亲诺曼（威廉?达福 Willem Dafoe 饰）是一家生物科技公司的老板，因自己公司生产的飞行器没得到军方首脑赏识而苦恼不堪。一次意外诺曼吸入神经毒气而具有了超能力，引发了自身邪恶的本性，骑着自己研发的飞行器去到处破坏、杀人。彼得化身的蜘蛛侠开始出击了！
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Wayo is accepted at the Kantaphat University, in the Faculty of Sciences; in the same institution he studies, Phana, a second-year boy he has always been in love with, though he never managed to talk to him. When Wayo has the chance to become the moon of his faculty, the two will begin to spend time together because Phana himself has been the moon of the medical school the previous year and must supervise the freshmen participating in the competition. Despite initially the strong character of Phana makes it difficult for Wayo any more simple interaction, the two slowly get closer and closer. So, Wayo began to visit friends of Phana, Beam and Kit; it is the latter who suddenly falls in love with Ming, Wayo's best friend, who begins to court him despite his initial haste.
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When a waitress is substituted for a belly dancer in a Greek restaurant, chaos and mayhem ensues before the owner is forced to change his old ways in order to prevent a major catastrophe.
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Dinda, who is considered strange by the village children because of her strength, accidentally injur